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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '011391d0670c636ec156580b4f0a37a3a59f44de41ebf2596af70b61eb2f2c43' 
  AND token = 'ZIQq9X0TfGZ3v8m4StAZ6smoz1UoNMpDr3GEvdzoAH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}