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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a02720c0f2b08cd57b3ceb428ce2496b13888bddc3f168f5b33f3f5f1150450' 
  AND token = '4ssT7JkRWITb8JM6PO+DsYBBSzunQDrdtq2JQwclBlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}