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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b94b14e2eb87afabf1998bee9e915bb73b3e62b03511ef3db9897f12fb006e' 
  AND token = 'RWQuJh2BYSs2gB4rJDSEo1eK6OM8za5p1HRCQpnBtdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}