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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a1d48356ea5ae5d971fd0af6eec1aa0db137a08279fcb055c8a57a39465b24' 
  AND token = 'SMZlcvrtI/to7C9P3jrEM95wAwyuLo3TmjMaZ7AADOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}