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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d25faa9a66903deb0de288d8f547faf7267ff175d41c1f688e854b22f1621f' 
  AND token = 'GQHTMQCuldwGoHkbz6gVRMC4lf9aXi7itUZ0tiN8OLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}