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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecef04c681e9218fcb9e2e3fb10ea01e516e421bf7b7c2de29e6088860fb0a17' 
  AND token = 'JHquk1Oa2qZQVsAV05pLCPBsXCwVNUGSxrGU2ErKJNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}