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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17dda4659a467eed9bf747ca6f8c19137cca5f0402542bdc8078a8d034acd456' 
  AND token = '49mya28nXtYhJTFnvcTU+ubdMSUgKXhFjhXy4o0uEWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}