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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a53a519c0e4f08956ace9a7dde38d07fa625391ee2a4f107e81a0c83ce15b8' 
  AND token = 'K/kDaO3+4dz7/cG1z/mANHQlwUKTzVeLfOkNyGOs6jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}