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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd0e1c49399627a754c6c8e70200119cde21cbadd92346ecb1c4ac9ded7cf86' 
  AND token = 'b71I+0v1U4Bc3Vc+URs/UWwOBv0ZkX8B5q5sVVeUCmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}