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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4455cae96467c27c57126cc1c2d417b3ca20cfaaac6c5b1ffab8d972f50c2810' 
  AND token = 'w39qkCgDUpxeoTy1+qD4FNopJBXUsx28CxwJ6KS1T1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}