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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '978c6b18aec2a5c4bb6f082dc2619c70268d77f320fb62f848efcc527d3d5c58' 
  AND token = '88t3KHAA/CWy5C7pkBIZ+aW+gt56M+YqC+QXnp6f7Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}