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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642d15aea728cab108735c0568fc77cf88ddc5f191a5655b943f38fb330d6ff7' 
  AND token = 'ZivMt1/lNvI6BqGDbmDIoaP3IPwvNt2nlw9bPRo26vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}