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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b747102df77bd5a3248f71700679a272ffb76b043a5de4d2eb742315606fea9' 
  AND token = 'NZBZWAsRdxz+igFv1srMQT+aWpMQbV3GtQY4CsJQzO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}