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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4176d34b0a6e2a14ddfb8b0cd1ef1e8f70b41b4d0343fa1764937d891d9018' 
  AND token = 'BHyjHk3oowXCM4HVZ1dp7w/8oWF1gJjRFdxdYai1l2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}