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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b4e7c08a5a4e90cf8ec4f0e528ddf216a7264ac795247ca0413db33b74f0f9f' 
  AND token = 'shrHVUpKaR+qqo4whPwCdOTMyCbx1TuzvRnM2skSPVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}