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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081b11ef92c7b96a94d700e11e8af1c4aa43b71997c8a854ace50f1e3f15578b' 
  AND token = 'gs69FPX37+q32tT0VhVu3ijCqdlp1nOx57bjn8tmsUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}