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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6242755d104ce04249531a7300a490befc61c3e0ca0b33eb84cee0a1ee15890' 
  AND token = 'dUhLg5oTqchgFR5+nh+b74wVKyq5d1lspvXIs0+lybM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}