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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e6f61bfc9e06bc070e88091330d20127eae93a37533a5b0cf40f22697a446f' 
  AND token = '973qWjgMc3JCVKn3VNCijof4mv+lKtIO8d3pfbghWoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}