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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f57607fe03d147f749f024c9387f971baf89190c66134c001edf3cfde485bc3' 
  AND token = 'aQX5xPjdOmLltvo4NO5G+ZPM9vEhb0jIs7X5jNS7Ia4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}