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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ac31bfa71e36ad08073f5a42d645a8ea3e4487e973e1fb3d4cd3bb0f56695c' 
  AND token = 'ZoY75+u9f9pSylqh4GIS+aeR5z1g7GTj38qDrSFzEWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}