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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8477208f2c2eb6cc2dcd6b180e00a80affd8c43d04731e77b934c76247a1bc' 
  AND token = 'QEely2Vyay/V5MI3wtv42+KwNRMzti4fv0dKOO7OtI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}