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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e29af1e4f4677448b71413272b2b078eeab380da75f60e3b86337611a3ce12e' 
  AND token = 'P6vf9u3H+VUWeQvOHNf9KGDTaxj/30eyhFjhcVTqb88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}