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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5046ee4ee43e2ca8e200606c74b731ddaa1b2e73401a2c82b25f8e6c077a3f6' 
  AND token = '7vgvI/HCZRWP8hYjQyAMpQ2RZnzX79uMshEgSPArMWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}