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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28661a6888550c4c2de2a462cdca04cfcb67619430ee371f7d73bcb6dfa4b6e4' 
  AND token = 'aThak2YGQ2tDp5Fz3hgEaYXj66pLk9zQkl6sQnZTd98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}