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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6cfbb36394538cf687faa2a07779b051234aa34052a558b91f59a2e8c987bfb' 
  AND token = '8RQWWdeVt9NYqxAmLxhV1TmydcO5AJ+LA2PF7EK+vgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}