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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad84e5543a55b57162826a154f824765530e5b6c0ef10f5e3d5da14e4e90006' 
  AND token = 'LuTYyWMtec2I4y4yAKGUSIEFzU412EgWMZpQLcRUo1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}