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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c47a1f9d7117142c687c3b58df986a9b6058b67f256533016f1c721e1a1ce702' 
  AND token = 'IU2FPiyJDgI9UhnbYjHMCsD0RehdlIMNNUI1NvhsAzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}