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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2913210120142b9ff49a5d215ae444b2cf8cad67f66333862d7fdbb999cdf2af' 
  AND token = '/Oo/HpBhUMjr4EKX61Y7GKRTcuWS44OBPUhrmeDKLE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}