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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2c244f322ff4c86889612bd8e36acb6d106d122e693419b52be12c1e189229' 
  AND token = '2rBum2iNPgxoiykrC9eDPRn7ojcvlMFra1Ca347ffH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}