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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edeb7fa0bdcd9fa6f3d72f8605882fd3eb160bc2d2cfcf3a996078edd7321f20' 
  AND token = 'u/OarVoUBisNTFOlFxnIbLrZilWKT4QE3tjDo56r+bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}