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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f34f0f93bfaca71a1bba857cf8cfade5644ccac71c7d6a45961d66e41d4b60' 
  AND token = 'YM4wGE/B/Ft4N9jW6JHlmnVg2TtoTmQW4o+0pohl0nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}