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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82203b1f0a31e7981e2d1cfae71d2fee8c473e866b8ef149060a71b07f0b83d2' 
  AND token = 'YS/DHt2OcadY5bRMhvdTSyxjkuWEj5Day6N8RdWp5Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}