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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c78e8f8bfb4307cf5cfebf0777c576123c643066029507ff852a771ae29f4d' 
  AND token = 'YYQNCFWxgqehc9s8FIO/0utiEW4ijX2rNO8MiIJhU/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}