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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a2cd81f9be08e8043fc1afd2a8a4ed1a0234d700771d015b2e5eb8f9e31b1d' 
  AND token = 'QDBC0iJCZrjenxzii8HOJoPPWJ6dND/DSgNefyoGnFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}