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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1c204dc087412d6e5c1bcfdf4618af04bd2d0a8a8d9d3a07444256acfc9807' 
  AND token = 'Z0WaWLwATp75mbnF/SJscewTT5Dw1+4Vwzg9/iKJ6bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}