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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c452fc12a726935a3dd51a02cbc2e63bf80eac1d032462ee5d025e6f2e85968' 
  AND token = 'Nuyjv3GDj+c3s9elnopRhSM3YfqAG6aaFrEhYoOG484=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}