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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201bd294bb17e6e717fd13de896c51b9793b9eb2d74c0038b0c47333c6af6248' 
  AND token = '+a3aRJYgaBblosfyErOltoTdF8ApUParVx0Gu+zC0Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}