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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c749d261cd671960c0da2169d9aa0145e718e32e6874fb1db6520cb2adbe9077' 
  AND token = '3X+XSEWgPw/tjI/DPuzLLnBZ0eVtHBEgd7F5nMNPQHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}