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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4ffcab51e7274e2b4518ee65ff80c605346663958b6fcd0de7ceba8dc119d1' 
  AND token = '2CBLB3w3/9EIEnt4i2zBCqveyxQVWCielpcWPd+27kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}