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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b51621f2ab7981a4066c4b1a8bc09208f0975c011b0e90d77d6da3a94e7583c' 
  AND token = 'blpFZ6Faa0oQPrDzJpQGtWaldD3xILfkCM1IXENhNjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}