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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04c4e7eff176e2d3e67184923c2da6246c634fa637ce614b94033d1c9fb3f489' 
  AND token = 'avkudiZWopAwMQr1BzBpVsqyuRJX+bvwBdg9rbQ4ggA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}