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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77fe8a6f86826b8f10be28f67b7e14b7132abeb10f77cf7ba5110164db9e1085' 
  AND token = 'FEU7B03ETKyhTtya8cCQlGiM3rkRDgOqQZYQnptPqQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}