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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03335f95501a0fd1c659dbbd5f74946c72764c6569f2012186bc26b9746c5d6' 
  AND token = 'hPxJnaNEPXcMZGFYYBR2J3/5mF9PLDjLrFNQ7dNk3dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}