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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d2df5c67d718aeb737632b84f0e5fdab34e1878ec4c32b34cb75aa2a081a59a' 
  AND token = 'K4fA/Zch4eFaxUxdU40pPFVRb0JZL+S7OFhPv4OcwgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}