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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78f7238874171d7766d36f2dffdb4eb59ad0143a31fc3bf3aaf5fabeefc24f4' 
  AND token = 'xdRKnWVeXn3RTYicjQ2UQrQ/l7ovmKKGI8qHaou1GXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}