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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea911df7c4968170f367b092fad8b40feaf8e355dc5d86290d68d73e37e82a2' 
  AND token = 'GVUK7OT6nlnvmTSwsfcXLgmioFh3ZDMfYO4UTR4s1TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}