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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c334d2fff85d290ae4df1aa9ecbdfebe5c4bbc646e5bb260be1d02d9a2505d01' 
  AND token = 'SU+9i+w2pfbQwdPz5dXvVhuhK2fiUfvc0vi2v1lSTJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}