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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8e3dc2e9448115ac41c79bb9ea639e9abb474e02424ea15e36a103764c3b84' 
  AND token = 'Fgu0XSVo9j0s5x5hKAZfWeDPPM6t603VR8g4cDfuZKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}