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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '391a98175305bdb2e23bf8b0c761bc2edd00f631fb35cb9f748c3bf9ca0c1063' 
  AND token = '7CbIHgTlXXxQWwUFmqMdjAsIgLc77dpAuy3L/WPnGEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}