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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c366254d7ae40138189003494e1c8eadcaf7680934f41767a322a0d1a44aa7' 
  AND token = 'ddrP3HGwkWERpjrMO5bfXQc/L6qVS0dJFV73rkAj8X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}